Photoredox Promoted Barbier-Type Reaction of Alkyl Iodides with N-Alkyl and N-Aryl Imines

Photoredox Promoted Barbier-Type Reaction of Alkyl Iodides with N-Alkyl and N-Aryl Imines Full article

Journal

Journal of Organic Chemistry
ISSN: 1520-6904 , E-ISSN: 0022-3263

Output data

Year: 2023, Volume: 88, Number: 2, Pages: 1260-1269 Pages count : 10 DOI: 10.1021/acs.joc.2c02598

Authors

Gladkov Anton A. ^1,2 , Levin Vitalij V. ¹ , Dilman Alexander D. ¹

Affiliations

1	N. D. Zelinsky Institute of Organic Chemistry, 119991 Moscow, Leninsky prosp. 47, Russian Federation
2	Lomonosov Moscow State University, Department of Chemistry, 119991, Moscow, Leninskie Gory 1-3, Russian Federation

The reaction of organozinc reagents with unactivated imines is accelerated when performed in the presence of a photocatalyst under blue light irradiation. Coordination between Lewis acidic zinc iodide and the imine is a key factor responsible for the reaction efficiency. The method can be carried out using alkyl iodides under Barbier conditions.

Gladkov A.A. , Levin V.V. , Dilman A.D.
Photoredox Promoted Barbier-Type Reaction of Alkyl Iodides with N-Alkyl and N-Aryl Imines
Journal of Organic Chemistry. 2023. V.88. N2. P.1260-1269. DOI: 10.1021/acs.joc.2c02598 WOS Scopus OpenAlex

Submitted:	Oct 27, 2022
Published online:	Jan 6, 2023

Web of science:	WOS:001038060400001
Scopus:	2-s2.0-85146086516
OpenAlex:	W4313624557

DB	Citing
OpenAlex	12
Web of science	10
Scopus	12