Synthesis of hybrid molecules based on thioglycolurils and 1,2,5-oxadiazoles via the Eschenmoser sulfide contraction

Synthesis of hybrid molecules based on thioglycolurils and 1,2,5-oxadiazoles via the Eschenmoser sulfide contraction Научная публикация

Журнал

Mendeleev Communications
ISSN: 1364-551X , E-ISSN: 0959-9436

Вых. Данные

Год: 2024, Том: 34, Номер: 1, Страницы: 122-125 Страниц : 4 DOI: 10.1016/j.mencom.2024.01.037

Авторы

Vinogradova Ekaterina E. ¹ , Larin Alexander A. ¹ , Gazieva Galina A. ¹

Организации

1	N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 119991 Moscow, Russian Federation

A simple synthesis of novel hybrid molecules containing methylidenehexahydroimidazo[4,5-d]imidazol-2(1H)-one and 1,2,5-oxadiazole moieties is based on the Eschenmoser sulfide contraction involving alkylative precoupling of thioglycolurils with 3(4)-bromoacetyl-1,2,5-oxadiazoles. The proposed method does not require using toxic PPh3 for sulfur extrusion. The synthesized compounds may serve as platforms for constructing both new bioactive and new high- energy compounds.

Vinogradova E.E. , Larin A.A. , Gazieva G.A.
Synthesis of hybrid molecules based on thioglycolurils and 1,2,5-oxadiazoles via the Eschenmoser sulfide contraction
Mendeleev Communications. 2024. V.34. N1. P.122-125. DOI: 10.1016/j.mencom.2024.01.037 WOS Scopus OpenAlex

Web of science:	WOS:001181748400001
Scopus:	2-s2.0-85184906076
OpenAlex:	W4391643481

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