Synthesis of functionalized phosphorus-substituted derivatives of γ-butyrolactone

Synthesis of functionalized phosphorus-substituted derivatives of γ-butyrolactone Full article

Journal

Russian Chemical Bulletin
ISSN: 1573-9171 , E-ISSN: 1066-5285

Output data

Year: 2024, Volume: 73, Number: 5, Pages: 1386-1393 Pages count : 8 DOI: 10.1007/s11172-024-4256-0

Authors

Bubnov Yu.N. ¹ , Prishchenko A.A. ² , Livantsov M.V. ² , Novikova O.P. ² , Livantsova L.I. ² , Baranin S.V. ¹

Affiliations

1	N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky prosp., 119991, Moscow, Russian Federation
2	Chemical Department, M. V. Lomonosov Moscow State University, Build. 3, 1 Leninskiye Gory, 119991, Moscow, Russian Federation

A convenient synthesis of functionalized phosphorus-substituted derivatives of γ-butyrolactone based on readily available γ-crotonolactone and trimethylsilyl esters of trivalent phosphorus acids has been developed. The addition of bis(trimethylsiloxy)phosphine to γ-crotonolactone proceeds regioselectively to give phosphonites containing γ-butyrolactone moieties, the subsequent functionalization of which leads to a variety of target derivatives. The resulting compounds are of interest as promising biologically active substances and water-soluble ligands.

Bubnov Y.N. , Prishchenko A.A. , Livantsov M.V. , Novikova O.P. , Livantsova L.I. , Baranin S.V.
Synthesis of functionalized phosphorus-substituted derivatives of γ-butyrolactone
Russian Chemical Bulletin. 2024. V.73. N5. P.1386-1393. DOI: 10.1007/s11172-024-4256-0 WOS Scopus OpenAlex

≡ Web of science:	WOS:001252371600021
≡ Scopus:	2-s2.0-85196528417
≡ OpenAlex:	W4399899435