Synthesis and antibacterial activity of new dimeric pyridinium chlorides based on 2,2-bis(hydroxymethyl)propane-1,3-diyl spacer Full article
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Russian Chemical Bulletin
ISSN: 1573-9171 , E-ISSN: 1066-5285 |
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| Output data | Year: 2020, Volume: 69, Number: 3, Pages: 620-623 Pages count : 4 DOI: 10.1007/s11172-020-2808-5 | ||
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Abstract:
New bispyridinium dichlorides based on 2,2-bis(hydroxymethyl)propane-1,3-diyl spacer were synthesized from pentaerythritol, 4-aminopyridine, and carboxylic acids. The resulting biocides possess a high antibacterial effect. The minimal inhibitory concentration (MIC) of these compounds against pathogenic bacteria, namely, gram-positive Methicillin-resistant Staphylococcus aureus (strain ATCC 25923) and gram-negative Escherichia coli (ATCC 25922) and Pseudomonas aeruginosa (ATCC 27853), was established. The influence of the alkyl substituent length in salts on their microbiological activity was studied.
Cite:
Vereshchagin A.N.
, Karpenko K.A.
, Egorov M.P.
Synthesis and antibacterial activity of new dimeric pyridinium chlorides based on 2,2-bis(hydroxymethyl)propane-1,3-diyl spacer
Russian Chemical Bulletin. 2020. V.69. N3. P.620-623. DOI: 10.1007/s11172-020-2808-5 WOS Scopus OpenAlex
Synthesis and antibacterial activity of new dimeric pyridinium chlorides based on 2,2-bis(hydroxymethyl)propane-1,3-diyl spacer
Russian Chemical Bulletin. 2020. V.69. N3. P.620-623. DOI: 10.1007/s11172-020-2808-5 WOS Scopus OpenAlex
Identifiers:
| Web of science: | WOS:000524864600028 |
| Scopus: | 2-s2.0-85083047284 |
| OpenAlex: | W3016063992 |