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Direct oxidation of alkanoic acids to lactones Full article

Journal Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science
ISSN: 2376-8444 , E-ISSN: 0568-5230
Output data Year: 1982, Volume: 31, Number: 10, Pages: 2041-2046 Pages count : 6 DOI: 10.1007/bf00950650
Authors Troyanskii E.I. 1 , Svitan'ko I.V. 1 , Nikishin G.I. 1
Affiliations
1 N. D. Zelinskii Institute of Organic Chemistry, Academy of Sciences of the USSR, Moscow

Abstract: 1. By the action of the Na2S2O8-CuCl2 system, alkanoic acids RR′CHCH(R″)CH2COOH convert into γ-lactones with high regioselectivity. 2. A reaction mechanism was proposed, including the formation from alkanoic acids of alkylcarbonyloxyl radicals, their rearrangement with 1,5-migration of the H atom into 3-carboxylalkyl radicals, and oxidative cyclization of the latter into γ-lactones.
Cite: Troyanskii E.I. , Svitan'ko I.V. , Nikishin G.I.
Direct oxidation of alkanoic acids to lactones
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science. 1982. V.31. N10. P.2041-2046. DOI: 10.1007/bf00950650 OpenAlex
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OpenAlex: W2950936553
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