Synthesis of new N-(diphosphonomethyl)-containing peptides on the base of tris(trimethylsilyl) phosphite

Synthesis of new N-(diphosphonomethyl)-containing peptides on the base of tris(trimethylsilyl) phosphite Научная публикация

Журнал

Russian Chemical Bulletin
ISSN: 1573-9171 , E-ISSN: 1066-5285

Вых. Данные

Год: 2022, Том: 71, Номер: 9, Страницы: 1976-1980 Страниц : 5 DOI: 10.1007/s11172-022-3616-x

Авторы

Prishchenko A.A. ¹ , Alekseev R.S. ¹ , Novikova O.P. ¹ , Livantsov M.V. ¹ , Livantsova L.I. ¹ , Baranin S.V. ²

Организации

1	M. V. Lomonosov Moscow State University, Department of Chemistry, Build. 3, 1 Leninskie Gory, 119991 Moscow, Russian Federation
2	N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky prosp., 119991 Moscow, Russian Federation

New functionalized N-(diphosphonomethyl)-containing peptides were synthesized in high yields by the reaction of tris(trimethylsilyl) phosphite with the appropriate N-formylpeptides under mild conditions in the presence of an effective catalyst, trimethylsilyl triflate. A catalytic scheme for the formation of the products was proposed. The resulting compounds are of interest as promising biologically active substances and effective ligands.

Prishchenko A.A. , Alekseev R.S. , Novikova O.P. , Livantsov M.V. , Livantsova L.I. , Baranin S.V.
Synthesis of new N-(diphosphonomethyl)-containing peptides on the base of tris(trimethylsilyl) phosphite
Russian Chemical Bulletin. 2022. V.71. N9. P.1976-1980. DOI: 10.1007/s11172-022-3616-x WOS Scopus OpenAlex

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