Chemodivergent Phototransformations of Green Fluorescent Protein Related Chromophores: Wavelength‐Dependent Photodimerization and Spirocyclization

Chemodivergent Phototransformations of Green Fluorescent Protein Related Chromophores: Wavelength‐Dependent Photodimerization and Spirocyclization Full article

Journal

Advanced Synthesis & Catalysis
ISSN: 1615-4169 , E-ISSN: 1615-4150

Output data

Year: 2025, Volume: 367, Number: 5, Article number : e202401001, Pages count : DOI: 10.1002/adsc.202401001

Authors

Opryshko Victoria E. ¹ , Ivanov Dmitrii S. ¹ , Danshina Anastasia A. ² , Krasnova Svetlana A. ¹ , Eshtukov‐Shcheglov Artur V. ¹ , Mikhaylov Andrey A. ^1,3 , Smirnov Alexander Yu. ^1,3 , Baranov Mikhail S. ^1,3

Affiliations

1	Institute of Bioorganic Chemistry Russian Academy of Sciences Miklukho-Maklaya 16/10 Moscow 117997 Russia
2	N. D. Zelinsky Institute of Organic Chemistry Russian Academy of Sciences 47 Leninsky prosp. Moscow 119991 Russian Federation
3	Pirogov Russian National Research Medical University Ostrovitianov 1 Moscow 117997 Russia

Benzylidene imidazolones with an ortho-sec-amino group undergo chemodivergent photochemical transformations, based on the wavelength of irradiation. Irradiation at 525 nm causes dimerization and the formation of cyclobutanes with two spiroatoms, related to dictazoles in 87–98% yield. In turn, irradiation at 365 nm provides access to spirocyclic indolines in 67–92% yield. Each of the processes proceeds with exclusive atom economy and chemoselectivity.

Opryshko V.E. , Ivanov D.S. , Danshina A.A. , Krasnova S.A. , Eshtukov‐Shcheglov A.V. , Mikhaylov A.A. , Smirnov A.Y. , Baranov M.S.
Chemodivergent Phototransformations of Green Fluorescent Protein Related Chromophores: Wavelength‐Dependent Photodimerization and Spirocyclization
Advanced Synthesis & Catalysis. 2025. V.367. N5. e202401001 . DOI: 10.1002/adsc.202401001 WOS OpenAlex

Web of science:	WOS:001364560900001
OpenAlex:	W4404235412

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