An efficient synthesis of new polyfunctional hexahydro pyrido[1,2-a]pyrazin-1-ones

An efficient synthesis of new polyfunctional hexahydro pyrido[1,2-a]pyrazin-1-ones Full article

Journal

Mendeleev Communications
ISSN: 1364-551X , E-ISSN: 0959-9436

Output data

Year: 2021, Volume: 31, Number: 2, Pages: 259-261 Pages count : 3 DOI: 10.1016/j.mencom.2021.03.039

Authors

Shmoylova Yana Yu. ¹ , Kovygin Yuri A. ¹ , Ledenyova Irina V. ¹ , Prezent Mikhail A. ² , Daeva Elena D. ² , Baranin Sergey V. ² , Shikhaliev Khidmet S. ¹

Affiliations

1	Voronezh State University, 394018 Voronezh, Russian Federation
2	N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 119991 Moscow, Russian Federation

New polyfunctional hydrogenated pyrido[1,2-a]pyrazin- 1-ones were obtained by regioselective recyclization of N-arylitaconimides with alkyl (3-oxopiperazin-2-ylidene)acetates. The supposed cascade reaction pathway involves the Michael addition of the nucleophile to an activated double bond and subsequent intramolecular transamidation of the intermediate with simultaneous recycling.

Shmoylova Y.Y. , Kovygin Y.A. , Ledenyova I.V. , Prezent M.A. , Daeva E.D. , Baranin S.V. , Shikhaliev K.S.
An efficient synthesis of new polyfunctional hexahydro pyrido[1,2-a]pyrazin-1-ones
Mendeleev Communications. 2021. V.31. N2. P.259-261. DOI: 10.1016/j.mencom.2021.03.039 WOS Scopus OpenAlex

≡ Web of science:	WOS:000635839800039
≡ Scopus:	2-s2.0-85104987614
≡ OpenAlex:	W3145598085