Somatic Antigens of Shigella. Structural Investigation on the O-Specific Polysaccharide Chain of Shigella Dysenteriae Type-2 Lipopolysaccharide

Somatic Antigens of Shigella. Structural Investigation on the O-Specific Polysaccharide Chain of Shigella Dysenteriae Type-2 Lipopolysaccharide Научная публикация

Журнал

European Journal of Biochemistry
ISSN: 0014-2956 , E-ISSN: 0945-5795

Вых. Данные

Год: 1977, Том: 76, Номер: 2, Страницы: 433-440 Страниц : 8 DOI: 10.1111/j.1432-1033.1977.tb11612.x

Авторы

DMITRIEV Boris A. ¹ , KNIREL Yuriy A. ¹ , KOCHETKOV Nikolay K. ¹ , HOFMAN Irihna L. ² , CAPEK Karel ³

Организации

1	Institut Organicheskoj Khimii im. N. D. Zelinskogo, Akademia Nauk, Leninskij Prospekt 47, Moskva, U.S.S.R. 117913
2	Institut Mikrobiologii i Epiderniologii Minzdrava, Upensky per, 12, Moskva K‐6, U.S.S.R.
3	Chemicko‐Technologická, Technická 1905, CS‐16000 Praha 6‐Dejvice, Czechoslovakia

The O-specific polysaccharide obtained from Shigella dysenteriae type-2 lipopolysaccharide by mild acid hydrolysis consisted of N-acetylgalactosamine, N-acetylglucosamine, d-galactose, d-glucose, and O-acetyl group in the ratio of 2:1:1:1:1. A number of oligosaccharides were obtained by deamination of the N-deacetylated polysaccharide and by Smith degradation of the both native and O-deacetylated polysaccharides. The identification of oligosaccharides along with methylation analysis and chromic anhydride oxidation showed that the polysaccharide was built up of the repeating pentasaccharide units whose proposed structure is given below:

DMITRIEV B.A. , KNIREL Y.A. , KOCHETKOV N.K. , HOFMAN I.L. , CAPEK K.
Somatic Antigens of Shigella. Structural Investigation on the O-Specific Polysaccharide Chain of Shigella Dysenteriae Type-2 Lipopolysaccharide
European Journal of Biochemistry. 1977. V.76. N2. P.433-440. DOI: 10.1111/j.1432-1033.1977.tb11612.x OpenAlex

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