Electrocatalytic cascade approach to the synthesis of dihydro-2'H,3H-spiro[1-benzofuran-2,5'-pyrimidines]

Electrocatalytic cascade approach to the synthesis of dihydro-2'H,3H-spiro[1-benzofuran-2,5'-pyrimidines] Full article

Journal

Chemistry of Heterocyclic Compounds
ISSN: 1573-8353 , E-ISSN: 0009-3122

Output data

Year: 2021, Volume: 57, Number: 6, Pages: 672-678 Pages count : 7 DOI: 10.1007/s10593-021-02966-8

Authors

Ryzhkov Fedor V. ¹ , Elinson Michail N. ¹ , Ryzhkova Yuliya E. ¹ , Vereshchagin Anatoly N. ¹ , Fakhrutdinov Artem N. ¹ , Egorov Mikhail P. ¹

Affiliations

1	N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky Ave, Moscow, 119991, Russia

Electrocatalytic cascade assembly of benzylidenebarbiturates and cyclohexane-1,3-diones in methanol in the presence of sodium bromide as mediator in an undivided cell results in the formation of dihydro-2'H,3H-spiro[1-benzofuran-2,5'-pyrimidines] in 72–85% yields. This electrochemical process occurs under mild conditions, and the isolation procedure after the reaction is simple. The structures of the final compounds were confirmed by 1H–13C HMBC spectroscopy.

Ryzhkov F.V. , Elinson M.N. , Ryzhkova Y.E. , Vereshchagin A.N. , Fakhrutdinov A.N. , Egorov M.P.
Electrocatalytic cascade approach to the synthesis of dihydro-2'H,3H-spiro[1-benzofuran-2,5'-pyrimidines]
Chemistry of Heterocyclic Compounds. 2021. V.57. N6. P.672-678. DOI: 10.1007/s10593-021-02966-8 WOS Scopus OpenAlex

Web of science:	WOS:000668264000004
Scopus:	2-s2.0-85108828680
OpenAlex:	W3176697527

DB	Citing
OpenAlex	6
Scopus	4
Web of science	6