Selective cleavage of glycosidic linkages Научная публикация
| Журнал |
Carbohydrate Research
ISSN: 1873-426X , E-ISSN: 0008-6215 |
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| Вых. Данные | Год: 1973, Том: 29, Номер: 2, Страницы: 451-457 Страниц : 7 DOI: 10.1016/s0008-6215(00)83031-1 | ||
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Реферат:
Benzyl 2-acetamido-2-deoxy-3-O-β-D-galactopyranosyl-α-D-glucopyranoside (1) was chosen as a model bioside to develop a standard procedure for the selective cleavage of glycosidic linkages in polysaccharides containing 2-amino-2-deoxyhexose residues. Treatment of 1 with hydrazine in the presence of hydrazine sulphate resulted in quantitative N-deacetylation with the formation of benzyl 2-amino-2-deoxy-3-O-β-D-galactopyranosyl-α-D-glucopyranoside (2). The galactosyl glycosidic linkage in 2 could be selectively cleaved by acid hydrolysis. Oxidation of 2 with periodate destroyed the galactose residue. Treatment of 2 with nitrous acid cleaved the 2-amino-2-deoxy-D-glucosyl linkage to give 2,5-anhydro-3-O-β-D-galactopyranosyl-D-mannose (3) and benzyl alcohol.
Библиографическая ссылка:
Dmitriev B.A.
, Knirel Y.A.
, Kochetkov N.K.
Selective cleavage of glycosidic linkages
Carbohydrate Research. 1973. V.29. N2. P.451-457. DOI: 10.1016/s0008-6215(00)83031-1 WOS Scopus OpenAlex
Selective cleavage of glycosidic linkages
Carbohydrate Research. 1973. V.29. N2. P.451-457. DOI: 10.1016/s0008-6215(00)83031-1 WOS Scopus OpenAlex
Идентификаторы БД:
| Web of science: | WOS:A1973R222300018 |
| Scopus: | 2-s2.0-15644366032 |
| OpenAlex: | W4247585738 |