C,N-chelated diaminocarbene platinum(II) complexes derived from 3,4-diaryl-1H-pyrrol-2,5-diimines and cis-dichlorobis(isonitrile)platinum(II): Synthesis, cytotoxicity, and catalytic activity in hydrosilylation reactions

C,N-chelated diaminocarbene platinum(II) complexes derived from 3,4-diaryl-1H-pyrrol-2,5-diimines and cis-dichlorobis(isonitrile)platinum(II): Synthesis, cytotoxicity, and catalytic activity in hydrosilylation reactions Full article

Journal

Journal of Organometallic Chemistry
ISSN: 1872-8561 , E-ISSN: 0022-328X

Output data

Year: 2020, Volume: 923, Article number : 121435, Pages count : DOI: 10.1016/j.jorganchem.2020.121435

Authors

Afanasenko Anastasiia M. ¹ , Chulkova Tatiana G. ² , Boyarskaya Irina A. ² , Islamova Regina M. ² , Legin Anton A. ³ , Keppler Bernhard K. ³ , Selivanov Stanislav I. ² , Vereshchagin Anatoly N. ⁴ , Elinson Michail N. ⁴ , Haukka Matti ⁵

Affiliations

1	Stratingh Institute for Chemistry University of Groningen Nijenborgh 4 9747 AG Groningen The Netherlands
2	Saint Petersburg State University, Institute of Chemistry, 7/9 Universitetskaya Nab., Saint Petersburg, 199034, Russia
3	Institute of Inorganic Chemistry, University of Vienna, Währinger Straße 42,1090, Vienna, Austria
4	N. D. Zelinsky Institute of Organic Chemistry, 47 Leninsky Prospect, Moscow, 119991, Russia
5	Department of Chemistry, University of Jyväskylä, P.O. Box 35, FI-40014, Jyväskylä, Finland

The reaction of 3,4-diaryl-1H-pyrrol-2,5-diimines with cis-dichlorobis(isonitrile)platinum(II) affords the C,N-chelated diaminocarbene platinum(II) complexes, which have been fully characterized including molecular spectroscopy, single crystal X-ray diffraction and DFT calculations. The obtained platinum(II) complexes are effective catalysts for the hydrosilylation of alkynes and alkenes. Thus, the reaction of phenylacetylene with triethoxysilane leads to the formation of α- and β-(E)-vinylsilanes, generating TON’s in the range of 103 to 104 and TOF’s in the range of 102 to 103 h−1. Also, the cross-linked silicones, possessing the luminescence properties, were obtained by the hydrosilylation reaction of vinyl- and hydride-containing polysiloxanes. Additionally, the efficiency of diaminocarbene platinum(II) complexes against CH1/PA-1, SW480, and A549 cancer cell lines has been demonstrated by in vitro cytotoxicity studies.

Afanasenko A.M. , Chulkova T.G. , Boyarskaya I.A. , Islamova R.M. , Legin A.A. , Keppler B.K. , Selivanov S.I. , Vereshchagin A.N. , Elinson M.N. , Haukka M.
C,N-chelated diaminocarbene platinum(II) complexes derived from 3,4-diaryl-1H-pyrrol-2,5-diimines and cis-dichlorobis(isonitrile)platinum(II): Synthesis, cytotoxicity, and catalytic activity in hydrosilylation reactions
Journal of Organometallic Chemistry. 2020. V.923. 121435 . DOI: 10.1016/j.jorganchem.2020.121435 WOS Scopus OpenAlex

Web of science:	WOS:000575167700002
Scopus:	2-s2.0-85088996483
OpenAlex:	W3045421284

DB	Citing
OpenAlex	13
Scopus	12
Web of science	10