Selective cleavage of glycosidic linkages: studies with the model compound benzyl 2-acetamido-2-deoxy-6-O-α-D-mannopyranosyl-α-D-glucopyranoside Full article
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Carbohydrate Research
ISSN: 1873-426X , E-ISSN: 0008-6215 |
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| Output data | Year: 1973, Volume: 30, Number: 1, Pages: 45-50 Pages count : 6 DOI: 10.1016/s0008-6215(00)82171-0 | ||
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Abstract:
N-Deacetylation of benzyl 2-acetamido-2-deoxy-6-O-α-D-mannopyranosyl-α-D-glucopyranoside (3) by alkaline hydrolysis, or hydrazinolysis in the presence of hydrazine sulphate, proceeds quantitatively to yield the amine 4. The mannosyl glycosidic linkage in 4 can be selectively hydrolysed by acid, whereas the 2-amino-2-deoxyhexosyl glycosidic linkage is selectively cleaved upon treatment with sodium nitrite in dilute acetic acid. Aspects of the selective cleavage of hexosaminoglycans are discussed.
Cite:
Dmitrieve B.A.
, Knirel Y.A.
, Kochetkov N.K.
Selective cleavage of glycosidic linkages: studies with the model compound benzyl 2-acetamido-2-deoxy-6-O-α-D-mannopyranosyl-α-D-glucopyranoside
Carbohydrate Research. 1973. V.30. N1. P.45-50. DOI: 10.1016/s0008-6215(00)82171-0 WOS Scopus OpenAlex
Selective cleavage of glycosidic linkages: studies with the model compound benzyl 2-acetamido-2-deoxy-6-O-α-D-mannopyranosyl-α-D-glucopyranoside
Carbohydrate Research. 1973. V.30. N1. P.45-50. DOI: 10.1016/s0008-6215(00)82171-0 WOS Scopus OpenAlex
Identifiers:
| Web of science: | WOS:A1973R381600005 |
| Scopus: | 2-s2.0-49549167921 |
| OpenAlex: | W2096199945 |