Реферат: The general electrocatalytic cascade approach was found to medicinally relevant spirobarbituric 2,3-dihydro-4H-furo[2,3-c]chromen-4-one scaffold. This new electrocatalytic fast and efficient reaction of benzylidenebarbiturates and 4-hydroxycoumarin in alcohols in the presence of alkali metal halides as mediators in an undivided cell results in the formation of the substituted unsymmetric spirobarbituric 2,3-dihydro-4H-furo[2,3-с]chromen-4-ones in 72–83% yields. This general and efficient approach avoids traditional recrystallization and chromatographic purification stages. According to screening molecular docking data, all synthesized compounds may be prominent for different medical applications, such as control pain, breast cancer therapies, and treatment of obesity, epilepsy, hypertension, cardiovascular disease and diabetes.

Библиографическая ссылка: Elinson M.N. , Vereshchagin A.N. , Ryzhkova Y.E. , Karpenko K.A. , Ryzhkov F.V. , Egorov M.P.
Electrocatalytic Cascade Selective Approach to 3-Aryl-2' H ,3 H ,4 H -Spiro{Furo[2,3- с ]Chromene-2,5'-Pyrimidine}-2',4,4',6'(1' H ,3' H )Tetraones and Its Automatic Screening Docking Studies
Polycyclic Aromatic Compounds. 2023. V.43. N9. P.8356-8370. DOI: 10.1080/10406638.2022.2149568 WOS Scopus OpenAlex

Идентификаторы БД:

Web of science:	WOS:000893774600001
Scopus:	2-s2.0-85144006507
OpenAlex:	W4311568459

Цитирование в БД:

БД	Цитирований
OpenAlex	2
Scopus	1
Web of science	1

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