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Synthesis of selectively protected α-(1→3)- and α-(1→5)-linked octasaccharide moiety bearing a Janus aglycone, related to the branching site of mycobacterial polysaccharides Научная публикация

Журнал Russian Chemical Bulletin
ISSN: 1573-9171 , E-ISSN: 1066-5285
Вых. Данные Год: 2022, Том: 71, Номер: 12, Страницы: 2740-2750 Страниц : 11 DOI: 10.1007/s11172-022-3703-z
Авторы Abronina P.I. 1 , Shvyrkina Yu.S. 1 , Zinin A.I. 1 , Chizhov A.O. 1 , Kononov L.O. 1
Организации
1 N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky prosp., 119991, Moscow, Russian Federation

Реферат: A novel selectively protected α-(1→3)- and α-(1→5)-linked branched octasaccharide based on arabinofuranose was synthesized via a convergent route as a glycoside with 4-(2-chloroethoxy)phenyl aglycone, belonging to the class of Janus aglycones. The obtained octasaccharide is related to the branching site of lipoarabinomannan and arabinogalactan of mycobacteria. The Janus aglycone moiety can play the role of not only a temporary protective group at the anomeric position of sugar, but also a pre-spacer for the synthesis of neoglycoconjugates useful in the design of new tools for diagnostics of tuberculosis.
Библиографическая ссылка: Abronina P.I. , Shvyrkina Y.S. , Zinin A.I. , Chizhov A.O. , Kononov L.O.
Synthesis of selectively protected α-(1→3)- and α-(1→5)-linked octasaccharide moiety bearing a Janus aglycone, related to the branching site of mycobacterial polysaccharides
Russian Chemical Bulletin. 2022. V.71. N12. P.2740-2750. DOI: 10.1007/s11172-022-3703-z WOS Scopus OpenAlex
Идентификаторы БД:
Web of science: WOS:000971659000018
Scopus: 2-s2.0-85148940805
OpenAlex: W4322484339
Цитирование в БД:
БД Цитирований
OpenAlex 7
Scopus 7
Web of science 7
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