3-Benzoyl-1′,3′,6-trimethyl-2′H,3H,4H-spiro[furo [3,2-c]pyran-2,5′-pyrimidine]-2′,4,4′,6′(1′H,3′H)-tetraone

3-Benzoyl-1′,3′,6-trimethyl-2′H,3H,4H-spiro[furo [3,2-c]pyran-2,5′-pyrimidine]-2′,4,4′,6′(1′H,3′H)-tetraone Full article

Journal

Molbank
ISSN: 1422-8599

Output data

Year: 2025, Volume: 2025, Number: 1, Article number : M1951, Pages count : DOI: 10.3390/m1951

Authors

Elinson Michail N. ¹ , Kalashnikova Varvara M. ¹ , Ryzhkova Yuliya E. ¹ , Rakitin Oleg A. ¹

Affiliations

1	N. D. Zelinsky Institute of Organic Chemistry Russian Academy of Sciences, 47 Leninsky Prospekt, 119991 Moscow, Russia

We describe an approach towards the synthesis of previously unknown 3-benzoyl-1′,3′,6-trimethyl-2′H,3H,4H-spiro[furo[3,2-c]pyran-2,5′-pyrimidine]-2′,4,4′,6′(1′H,3′H)-tetraone. The presented method is based on the cyclization of 5-(1-(4-hydroxy-6-methyl-2-oxo-2H-pyran-3-yl)-2-oxo-2-phenylethyl)-1,3-dimethylpyrimidine-2,4,6(1H,3H,5H)-trione. It was shown that the presented reaction proceeds through the stage of bromination of the starting compound followed by O-nucleophilic attack. The structures of the obtained compound were established by 1H, 13C NMR and IR spectroscopy, and high-resolution mass spectrometry.

Elinson M.N. , Kalashnikova V.M. , Ryzhkova Y.E. , Rakitin O.A.
3-Benzoyl-1′,3′,6-trimethyl-2′H,3H,4H-spiro[furo [3,2-c]pyran-2,5′-pyrimidine]-2′,4,4′,6′(1′H,3′H)-tetraone
Molbank. 2025. V.2025. N1. M1951 . DOI: 10.3390/m1951 WOS Scopus OpenAlex

Web of science:	WOS:001453088500001
Scopus:	2-s2.0-105001415669
OpenAlex:	W4406399711

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