Synthesis of S-substituted 5-sulfonylmethyl(ethyl)-1,3,4-thiadiazol-2-amines | Sciact

Synthesis of S-substituted 5-sulfonylmethyl(ethyl)-1,3,4-thiadiazol-2-amines Научная публикация

Журнал

Chemistry of Heterocyclic Compounds
ISSN: 1573-8353 , E-ISSN: 0009-3122

Вых. Данные

Год: 2022, Том: 58, Номер: 10, Страницы: 514-517 Страниц : 4 DOI: 10.1007/s10593-022-03121-7

Авторы

Serkov Sergei A. ¹ , Sigay Natalya V. ¹ , Kostikova Natalya N. ¹ , Fedorov Aleksander E. ¹ , Tyurin Anton P. ² , Gazieva Galina A. ¹

Организации

1	N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky Ave., Moscow 119991, Russia;
2	Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 16/10 Miklukho-Maklaya St., Moscow 117997, Russia

A series of 1,3,4-thiadiazol-2-amines with substituents containing SO2 group located at position 5 were obtained in good yields (63–81%) by cyclization of aryl(benzyl)sulfonylacetic or aryl(benzyl)sulfonylpropionic acids with thiosemicarbazide in refluxing POCl3.

Serkov S.A. , Sigay N.V. , Kostikova N.N. , Fedorov A.E. , Tyurin A.P. , Gazieva G.A.
Synthesis of S-substituted 5-sulfonylmethyl(ethyl)-1,3,4-thiadiazol-2-amines
Chemistry of Heterocyclic Compounds. 2022. V.58. N10. P.514-517. DOI: 10.1007/s10593-022-03121-7 WOS Scopus OpenAlex

≡ Web of science:	WOS:000875806200003
≡ Scopus:	2-s2.0-85146404700
≡ OpenAlex:	W4307821107