Novel naphthalene-based bis-pyridinium compounds with pronounced antibacterial activity

Novel naphthalene-based bis-pyridinium compounds with pronounced antibacterial activity Научная публикация

Журнал

Mendeleev Communications
ISSN: 1364-551X , E-ISSN: 0959-9436

Вых. Данные

Год: 2022, Том: 32, Номер: 5, Страницы: 606-608 Страниц : 3 DOI: 10.1016/j.mencom.2022.09.012

Авторы

Frolov Nikita A. ¹ , Smirnov Vladimir A. ^2,1 , Detusheva Elena V. ³ , Vereshchagin Anatoly N. ¹

Организации

1	N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 119991 Moscow, Russian Federation
2	D. I. Mendeleev University of Chemical Technology of Russia, 125047 Moscow, Russian Federation
3	State Research Center for Applied Microbiology & Biotechnology, 142279 Obolensk, Moscow Region, Russian Federation

Novel para-substituted bis-pyridinium compounds containing 2,7-dioxynaphthalene spacer were synthesized in two simple steps from the corresponding dihydroxy-naphthalene. The microbiological study on five reference (E. coli ATCC 25922, K. pneumoniae ATCC 70060, S. aureus ATCC 43300, P. aeruginosa ATCC27853, and A. baumannii ATCC 15308) and five clinical (E. coli B-3421/19,K. pneumoniae B-2523/18, S. aureus B-8648, P. aeruginosa B-2099/18 and A. baumannii B-2926/18) bacterial strains showed promising range of antibacterial properties for these biocides, compared to modern sanitizers.

Frolov N.A. , Smirnov V.A. , Detusheva E.V. , Vereshchagin A.N.
Novel naphthalene-based bis-pyridinium compounds with pronounced antibacterial activity
Mendeleev Communications. 2022. V.32. N5. P.606-608. DOI: 10.1016/j.mencom.2022.09.012 WOS Scopus OpenAlex

Web of science:	WOS:000874166100012
Scopus:	2-s2.0-85139288786
OpenAlex:	W4302759609

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