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Light Scattering in Non-aqueous Solutions of Low-Molecular-Mass Compounds: Application for Supramer Analysis of Reaction Solutions Full article

Journal Journal of Solution Chemistry
ISSN: 0095-9782 , E-ISSN: 1572-8927
Output data Year: 2020, Volume: 49, Number: 5, Pages: 629-644 Pages count : 16 DOI: 10.1007/s10953-020-00977-1
Authors Orlova Anna V. 1 , Laptinskaya Tatiana V. 2 , Malysheva Nelly N. 1 , Kononov Leonid O. 3,1
Affiliations
1 N.D. Zelinsky Institute of Organic Chemistry of the Russian Academy of Sciences, Moscow, Russia
2 Department of Physics, M.V. Lomonosov Moscow State University, Moscow, Russia
3 Moscow Institute of Physics and Technology (National Research University), Moscow Region, Russia

Abstract: The use of static and dynamic light scattering (SLS and DLS, respectively) for chraracterization of solutions (0.005–0.20 mol·L− 1) of a series of carbohydrate-based low-molecular-mass compounds (glycosyl donors for chemical glycosylation) in anhydrous acetonitrile is described. The DLS data obtained suggest that, in the cases studied, the solute molecules form different supramolecular assemblies (supramers) with variable hydrodynamic radii. Analysis of concentration dependences of complementary SLS data for these solutions revealed that solvent quality may change dramatically with concentration and with the nature of solute. These results suggest that a combination of SLS and DLS is a valuable analytical tool for the supramer analysis of reaction solutions, which is useful for the rational selection of optimal concentrations for performing glycosylation reactions.
Cite: Orlova A.V. , Laptinskaya T.V. , Malysheva N.N. , Kononov L.O.
Light Scattering in Non-aqueous Solutions of Low-Molecular-Mass Compounds: Application for Supramer Analysis of Reaction Solutions
Journal of Solution Chemistry. 2020. V.49. N5. P.629-644. DOI: 10.1007/s10953-020-00977-1 WOS Scopus OpenAlex
Identifiers:
Web of science: WOS:000529761400001
Scopus: 2-s2.0-85085099864
OpenAlex: W3023651482
Citing:
DB Citing
OpenAlex 13
Scopus 12
Web of science 12
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