A Facile Stereoselective Bis‐Trifluoromethylselenolation Reaction of Alkynes with AgSeCF3 and N‐Bromosuccinimide

A Facile Stereoselective Bis‐Trifluoromethylselenolation Reaction of Alkynes with AgSeCF3 and N‐Bromosuccinimide Full article

Journal

Asian Journal of Organic Chemistry
ISSN: 2193-5815 , E-ISSN: 2193-5807

Output data

Year: 2022, Volume: 11, Number: 8, Article number : e202200319, Pages count : DOI: 10.1002/ajoc.202200319

Authors

Wang Zhenyu ^1,2 , Cao Chengyao Kimmy ² , Tretyakov Evgeny ³ , Liu Wei ¹ , Chen Chao ²

Affiliations

1	College of Science, Tianjin University of Science and Technology, Tianjin, 300457 P. R. China
2	Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology (Ministry of Education, MOE), Department of Chemistry, Tsinghua University, Beijing, 100084 Chinа
3	N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Leninsky Ave. 47, Moscow, 119991 Russian Federation

A facile stereoselective bis-trifluoromethylselenolation reaction of alkyne derivatives was realized for the first time. The reaction of alkyne derivatives and AgSeCF3 was found to proceed in the presence of N-bromosuccinimide and water in tetrahydrofuran and afforded bis-trifluoromethylselenolated products in moderate-to-excellent yields. The new methodology enables one-pot synthesis with a broad substrate range.

Wang Z. , Cao C.K. , Tretyakov E. , Liu W. , Chen C.
A Facile Stereoselective Bis‐Trifluoromethylselenolation Reaction of Alkynes with AgSeCF3 and N‐Bromosuccinimide
Asian Journal of Organic Chemistry. 2022. V.11. N8. e202200319 . DOI: 10.1002/ajoc.202200319 WOS Scopus OpenAlex

Web of science:	WOS:000823111500001
Scopus:	2-s2.0-85133930736
OpenAlex:	W4283207074

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