Route to pyrrolo[1,2-a]quinoxalines via a furan ring opening-pyrrole ring closure sequence

Route to pyrrolo[1,2-a]quinoxalines via a furan ring opening-pyrrole ring closure sequence Full article

Journal

Tetrahedron Letters
ISSN: 0040-4039 , E-ISSN: 1873-3581

Output data

Year: 2020, Volume: 61, Number: 9, Article number : 151532, Pages count : DOI: 10.1016/j.tetlet.2019.151532

Authors

Zelina Elena Y. ¹ , Nevolina Tatyana A. ¹ , Sorotskaja Ludmila N. ² , Skvortsov Dmitry A. ^3,4 , Trushkov Igor V. ^5,6 , Uchuskin Maxim G. ¹

Affiliations

1	Perm State University, Bukireva St. 15, Perm 614990, Russian Federation
2	Kuban State Technological University, Moskovskaya St. 2, Krasnodar 350072, Russian Federation
3	Higher School of Economics, Myasnitskaya St. 13, Moscow 101000, Russian Federation
4	M. V. Lomonosov Moscow State University, Leninskie Gory 1-3, Moscow 119991, Russian Federation
5	D. Rogachev National Research Center of Pediatric Hematology, Oncology and Immunology, Samory Mashela St. 1, Moscow 117997, Russian Federation
6	N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Leninsky pr. 47, Moscow 119991, Russian Federation

A method was developed for the synthesis of pyrrolo[1,2-a]quinoxalines based on an acid-promoted furan ring opening of readily accessible N-(furan-2-ylmethyl)-2-nitroanilines or their heterocyclic analogues followed by a key reductive Paal-Knorr cyclization of the corresponding nitro-1,4-diketones.

Zelina E.Y. , Nevolina T.A. , Sorotskaja L.N. , Skvortsov D.A. , Trushkov I.V. , Uchuskin M.G.
Route to pyrrolo[1,2-a]quinoxalines via a furan ring opening-pyrrole ring closure sequence
Tetrahedron Letters. 2020. V.61. N9. 151532 . DOI: 10.1016/j.tetlet.2019.151532 WOS Scopus OpenAlex

Web of science:	WOS:000517855700006
Scopus:	2-s2.0-85076863111
OpenAlex:	W2996084608

DB	Citing
OpenAlex	6
Scopus	6
Web of science	5