Umpolung of Enamines: An Overview on Strategies and Synthons Review
| Journal |
Synlett
ISSN: 0936-5214 , E-ISSN: 1437-2096 |
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| Output data | Year: 2020, Volume: 31, Number: 05, Pages: 439-449 Pages count : 11 DOI: 10.1055/s-0037-1610741 | ||||||
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Abstract:
Umpolung strategies are of considerable interest to organic chemists because they provide alternative synthetic routes to those imposed by the natural polarity of classical synthons. Reverse-polarity reactions of aldehydes, α,β-unsaturated carbonyl compounds, and imines are deeply embedded in the methodology of organic synthesis. In recent years, umpolung of enols and enamines has received much attention as a novel strategy to access α-substituted ketones. Here, state-of-the-art approaches to umpolung of enamine reactivity are discussed, with a particular focus on recent developments in this field from the author’s research group.
Cite:
Sukhorukov A.Y.
Umpolung of Enamines: An Overview on Strategies and Synthons
Synlett. 2020. V.31. N05. P.439-449. DOI: 10.1055/s-0037-1610741 WOS Scopus OpenAlex
Umpolung of Enamines: An Overview on Strategies and Synthons
Synlett. 2020. V.31. N05. P.439-449. DOI: 10.1055/s-0037-1610741 WOS Scopus OpenAlex
Identifiers:
| Web of science: | WOS:000518641700004 |
| Scopus: | 2-s2.0-85081267359 |
| OpenAlex: | W2999840578 |