Sciact
  • EN
  • RU

N-[3-(Chloromethyl)-1,2-benzisoxazol-5-yl]acetamide Full article

Journal Molbank
ISSN: 1422-8599
Output data Year: 2022, Volume: 2022, Number: 2, Article number : M1389, Pages count : DOI: 10.3390/m1389
Authors Khodot Evgeniy N. 1 , Rakitin Oleg A. 1
Affiliations
1 N. D. Zelinsky Institute of Organic Chemistry Russian Academy of Sciences, 47 Leninsky Prospekt, 119991 Moscow, Russia

Abstract: Functionally substituted 1,2-benzisoxazoles are very important and promising heterocycles with various pharmacological activities. Benzoxazoles containing reactive 3-chloromethyl and 5-amino groups are practically unexplored derivatives in this series. In this communication, the simple method for the synthesis of N-[3-(chloromethyl)-1,2-benzisoxazol-5-yl]acetamide which is an interesting precursor for the preparation of a series of 3,5-disubstituted benzoxazoles was described. The structure of the synthesized compound was established by elemental analysis, high-resolution mass spectrometry, 1H, 13C NMR and IR spectroscopy, and mass spectrometry.
Cite: Khodot E.N. , Rakitin O.A.
N-[3-(Chloromethyl)-1,2-benzisoxazol-5-yl]acetamide
Molbank. 2022. V.2022. N2. M1389 . DOI: 10.3390/m1389 WOS Scopus OpenAlex
Identifiers:
Web of science: WOS:000816169000001
Scopus: 2-s2.0-85132766421
OpenAlex: W4283029641
Citing:
DB Citing
OpenAlex Нет цитирований
Scopus 1
Altmetrics: