Bioinspired Non‐Heme Mn Catalysts for Regio‐ and Stereoselective Oxyfunctionalizations with H2O2

Bioinspired Non‐Heme Mn Catalysts for Regio‐ and Stereoselective Oxyfunctionalizations with H2O2 Full article

Journal

Chemistry: A European Journal
ISSN: 0947-6539 , E-ISSN: 1521-3765

Output data

Year: 2023, Volume: 29, Number: 66, Article number : e202302772, Pages count : DOI: 10.1002/chem.202302772

Authors

Ottenbacher Roman V. ¹ , Bryliakova Anna A. ^2,3 , Kurganskii Vladimir I. ³ , Prikhodchenko Petr V. ⁴ , Medvedev Alexander G. ⁴ , Bryliakov Konstantin Petrovich ³

Affiliations

1	Boreskov Institute of Catalysis SB RAS, Mechanisms of Catalytic Reactions, RUSSIAN FEDERATION
2	Novosibirsk State University, Pirogova 2, Novosibirsk, 630090 Russian Federation
3	Zelinsky Institute of Organic Chemistry RAS, Leninsky Pr. 47, Moscow, 119991 Russian Federation
4	FSBIS N S Kurnakov Institute of General and Inorganic Chemistry of the Russian Academy of Sciences, Peroxolab, RUSSIAN FEDERATION

In recent years, metalloenzymes-mediated highly selective oxidations of organic substrates under mild conditions have been inspiration for developing synthetic bioinspired catalyst systems, capable of conducting such processes in the laboratory (and, in the future, in industry), relying on easy-to-handle and environmentally benign oxidants such as H2O2. To date, non-heme manganese complexes with chiral bis-amino-bis-pyridylmethyl and structurally related ligands are considered as possessing the highest synthetic potential, having demonstrated the ability to mediate a variety of chemo- and stereoselective oxidative transformations, such as epoxidations, C(sp3)-H hydroxylations and ketonizations, oxidative desymmetrizations, kinetic resolutions, etc. Furthermore, in the past few years non-heme Mn based catalysts have become the major platform for studies focused on getting insight into the molecular mechanisms of oxidant activation and (stereo)selective oxygen transfer, testing non-traditional hydroperoxide oxidants, engineering catalytic sites with enzyme-like substrate recognition-based selectivity, exploration of catalytic regioselectivity trends in the oxidation of biologically active substrates of natural origin. This contribution summarizes the progress in manganese catalyzed C-H oxygenative transformations of organic substrates, achieved essentially in the past 5 years (late 2018–2023).

Ottenbacher R.V. , Bryliakova A.A. , Kurganskii V.I. , Prikhodchenko P.V. , Medvedev A.G. , Bryliakov K.P.
Bioinspired Non‐Heme Mn Catalysts for Regio‐ and Stereoselective Oxyfunctionalizations with H2O2
Chemistry: A European Journal. 2023. V.29. N66. e202302772 . DOI: 10.1002/chem.202302772 WOS Scopus OpenAlex

Web of science:	WOS:001084914600001
Scopus:	2-s2.0-85174191155
OpenAlex:	W4386251398

DB	Citing
OpenAlex	23
Scopus	19
Web of science	19