N-Amination of Pyrazoles: a General Approach

N-Amination of Pyrazoles: a General Approach Full article

Journal

Mendeleev Communications
ISSN: 1364-551X , E-ISSN: 0959-9436

Output data

Year: 1993, Volume: 3, Number: 3, Article number : 111, Pages count : DOI: 10.1070/mc1993v003n03abeh000247

Authors

Vinogradov Vasilii M. ¹ , Dalinger Igor L. ¹ , Shevelev Svyatoslav A. ¹

Affiliations

1	N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 117913 Moscow, Russian Federation

A general approach to N-amination of pyrazoles, allowing the synthesis of previously inaccessible N-aminopyrazoles with electron-acceptor substituents in the ring, has been proposed, consisting of treatment of the pyrazoles with hydroxylamine-O-sulfonic acid in aqueous media at controlled pH depending on pKa of the pyrazole.

Vinogradov V.M. , Dalinger I.L. , Shevelev S.A.
N-Amination of Pyrazoles: a General Approach
Mendeleev Communications. 1993. V.3. N3. 111 . DOI: 10.1070/mc1993v003n03abeh000247 Scopus OpenAlex

≡ Scopus:	2-s2.0-84988963025
≡ OpenAlex:	W1999477754