A general method of preparation of N-diformylmethylazoles and cycloimonium diformyl methylides

A general method of preparation of N-diformylmethylazoles and cycloimonium diformyl methylides Full article

Journal

ChemPlusChem
ISSN: 1212-6950 , E-ISSN: 0010-0765

Output data

Year: 1988, Volume: 53, Number: 7, Pages: 1519-1528 Pages count : 10 DOI: 10.1135/cccc19881519

Authors

Král Vladimír ¹ , Semenov Viktor Vladimirovich ² , Kanishchev Mikhail Ivanovich ² , Arnold Zdeněk ¹ , Shevelev Svyatoslav Arkadievich ² , Fainzilberg Albert Aleksandrovich ²

Affiliations

1	Institute of Organic Chemistry and Biochemistry, Czechoslovak Academy of Sciences, 166 10 Prague 6 Czechoslovakia
2	N.D. Zelinsky Institute of Organic Chemistry, Academy of Sciences of the U.S.S.R., Moscow, B-334, U.S.S.R.

Formylation of easily accessible heteroarylacetic acids (R-CH2COOH, R = imidazole, pyrazole, tetrazole, pyridine) afforded in high yields the corresponding trimethinium salts R-C(=CH-N(CH3)2)CH=N(CH3)2)n+ nX- which on alkaline hydrolysis were converted into N-diformylmethylazoles R-C(CHO)=CH-OH. Their quaternization gave cycloimonium diformyl methylides.

Král V. , Semenov V.V. , Kanishchev M.I. , Arnold Z. , Shevelev S.A. , Fainzilberg A.A.
A general method of preparation of N-diformylmethylazoles and cycloimonium diformyl methylides
ChemPlusChem. 1988. V.53. N7. P.1519-1528. DOI: 10.1135/cccc19881519 OpenAlex

≡ OpenAlex:

W2047192859