Facile redox synthesis of azoxyfuroxans

Facile redox synthesis of azoxyfuroxans Full article

Journal

Tetrahedron
ISSN: 0040-4020 , E-ISSN: 1464-5416

Output data

Year: 2025, Volume: 188, Pages: 134957 Pages count : 1 DOI: 10.1016/j.tet.2025.134957

Authors

Sidunets Yuri A. ¹ , Melekhina Valeriya G. ¹ , Fershtat Leonid L. ¹

Affiliations

1	N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Science, Leninsky Prosp., 47, Moscow, 119991, Russian Federation

Herein, we report on an efficient two-step redox approach for the preparation of azoxyfuroxans via chemoselective reduction of the readily available 4-nitrofuroxans followed by NaIO4-mediated oxidative coupling of thus formed hydroxylamines. The established protocol is operationally simple, does not require exhaustive chromatography purification and enables a preparation of a wide range of target azoxyfuroxans. Additionally, our method is suitable for the synthesis of other representative azoxy compounds incorporating furazan, pyridine or benzyl moieties, confirming its synthetic potential in organic chemistry.

Sidunets Y.A. , Melekhina V.G. , Fershtat L.L.
Facile redox synthesis of azoxyfuroxans
Tetrahedron. 2025. V.188. P.134957. DOI: 10.1016/j.tet.2025.134957 WOS OpenAlex

Web of science:	WOS:001587190300001
OpenAlex:	W4414552135

Пока нет цитирований