Azo Dyes and the Microbial World: Synthesis, Breakdown, and Bioactivity

Azo Dyes and the Microbial World: Synthesis, Breakdown, and Bioactivity Full article

Journal

Microbiology Research
ISSN: 2036-7481

Output data

Year: 2025, Volume: 16, Number: 5, Article number : 100, Pages count : DOI: 10.3390/microbiolres16050100

Authors

Dembitsky Valery M. ¹ , Terent’ev Alexander O. ¹

Affiliations

1	N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Leninsky Prospect, 47, 119334 Moscow, Russia

This review discusses natural and synthetic azo compounds found in bacteria, fungal endophytes, fungi, plants, and invertebrates. More than 100 of these compounds have demonstrated significant pharmacological activity, including antitumor, antimicrobial, and antibacterial effects. Using mathematical algorithms and the PASS program, researchers predict new potential applications based on their structure–activity relationships. This review emphasizes the importance of natural azo compounds as promising drug prototypes and key players in drug discovery. It also explores the synthesis and degradation of azo dyes and their potential uses in medicine, food, cosmetics, and related fields. Additionally, the role of microorganisms in producing natural azo compounds and their synthetic counterparts is examined, showcasing their potential in drug development and human health advancements.

Dembitsky V.M. , Terent’ev A.O.
Azo Dyes and the Microbial World: Synthesis, Breakdown, and Bioactivity
Microbiology Research. 2025. V.16. N5. 100 . DOI: 10.3390/microbiolres16050100 WOS OpenAlex

Web of science:	WOS:001496469900001
OpenAlex:	W4410444807

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