Nitropyridines in the Synthesis of Bioactive Molecules

Nitropyridines in the Synthesis of Bioactive Molecules Full article

Journal

Pharmaceuticals
ISSN: 1424-8247

Output data

Year: 2025, Volume: 18, Number: 5, Article number : 692, Pages count : DOI: 10.3390/ph18050692

Authors

Starosotnikov Alexey ¹ , Bastrakov Maxim ¹

Affiliations

1	N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Leninsky Prosp. 47, 19991 Moscow, Russia

Pyridines are one of the most important and promising classes of N-heterocycles actively studied in modern organic and medicinal chemistry; in particular, pyridine is a privileged structural motif in drug design. From a synthetic organic chemistry perspective, nitropyridines can be considered as convenient and readily available precursors for a wide range of mono- and polynuclear heterocyclic systems demonstrating diverse activities, such as antitumor, antiviral, anti-neurodegenerative, etc. This review is an analysis of the literature on the use of nitropyridines for the synthesis of biologically active compounds, covering the period from 2015 to the present.

Starosotnikov A. , Bastrakov M.
Nitropyridines in the Synthesis of Bioactive Molecules
Pharmaceuticals. 2025. V.18. N5. 692 . DOI: 10.3390/ph18050692 WOS Scopus OpenAlex

Web of science:	WOS:001495723000001
Scopus:	2-s2.0-105006599389
OpenAlex:	W4410156639

DB	Citing
OpenAlex	1
Web of science	1
Scopus	1