Imine-based synthesis of functionalized phosphorus-containing carboxamides

Imine-based synthesis of functionalized phosphorus-containing carboxamides Full article

Journal

Russian Chemical Bulletin
ISSN: 1573-9171 , E-ISSN: 1066-5285

Output data

Year: 2025, Volume: 74, Number: 1, Pages: 171-189 Pages count : 19 DOI: 10.1007/s11172-025-4513-x

Authors

Bubnov Yu.N. ^1,2 , Prishchenko A.A. ³ , Livantsov M.V. ³ , Novikova O.P. ³ , Livantsova L.I. ³ , Baranin S.V. ²

Affiliations

1	A. N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, Build. 1, 28 ul. Vavilova, 119991, Moscow, Russian Federation
2	N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky prosp., 119991, Moscow, Russian Federation
3	M. V. Lomonosov Moscow State University, Chemical Department, Build. 3, 1 Leninskiye Gory, 119991, Moscow, Russian Federation

Convenient syntheses of functionalized phosphorus-containing carboxamides based on the reaction of adducts of imines and carboxylic acid chlorides with trimethylsilyl esters of trivalent phosphorus acids have been developed. Adducts ClCH(Ar)—N(R)C(O)R′ are convenient synthons for the preparation of the target phosphorus-containing carboxamides bearing P(O)—C—N—C(O) moieties. The resulting compounds contain polar amide and phosphoryl moieties, have potential biological activity, and are also of interest as effective extractants and polydentate chelating ligands.

Bubnov Y.N. , Prishchenko A.A. , Livantsov M.V. , Novikova O.P. , Livantsova L.I. , Baranin S.V.
Imine-based synthesis of functionalized phosphorus-containing carboxamides
Russian Chemical Bulletin. 2025. V.74. N1. P.171-189. DOI: 10.1007/s11172-025-4513-x WOS Scopus OpenAlex

≡ Web of science:	WOS:001452513200021
≡ Scopus:	2-s2.0-105001404597
≡ OpenAlex:	W4408935611