Oxirane-based synthesis of functionalized derivatives of 2-hydroxyalkyl-substituted organophosphorus acids

Oxirane-based synthesis of functionalized derivatives of 2-hydroxyalkyl-substituted organophosphorus acids Full article

Journal

Russian Chemical Bulletin
ISSN: 1573-9171 , E-ISSN: 1066-5285

Output data

Year: 2025, Volume: 74, Number: 2, Pages: 489-502 Pages count : 14 DOI: 10.1007/s11172-025-4541-6

Authors

Bubnov Yu.N. ^1,2 , Prishchenko A.A. ³ , Livantsov M.V. ³ , Novikova O.P. ³ , Livantsova L.I. ³ , Baranin S.V. ²

Affiliations

1	A. N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, Build. 1, 28 ul. Vavilova, 119991, Moscow, Russian Federation
2	N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky prosp., 119991, Moscow, Russian Federation
3	Chemical Department, M. V. Lomonosov Moscow State University, Build. 3, 1 Leninskiye Gory, 119991, Moscow, Russian Federation

Convenient syntheses of functionalized 2-hydroxyalkyl-substituted organophosphorus acids and their derivatives based on nucleophilic addition of trimethylsilyl esters of tricoordinated phosphorus acids to functionalized oxiranes have been developed. 2-Trimethylsiloxyalkyl-substituted phosphonites are effective synthons for the production of new functionalized 2-hydroxyalkyl-substituted organophosphorus acids bearing amino, carboxy or sulfo groups. The resulting compounds are of interest as potential bioactive substances, promising extractants and polydentate ligands.

Bubnov Y.N. , Prishchenko A.A. , Livantsov M.V. , Novikova O.P. , Livantsova L.I. , Baranin S.V.
Oxirane-based synthesis of functionalized derivatives of 2-hydroxyalkyl-substituted organophosphorus acids
Russian Chemical Bulletin. 2025. V.74. N2. P.489-502. DOI: 10.1007/s11172-025-4541-6 WOS Scopus OpenAlex

≡ Web of science:	WOS:001455386500007
≡ Scopus:	2-s2.0-105001289111
≡ OpenAlex:	W4408973294