Synthesis of functionalized mono-, bis-, and tris(spirophosphoranyl) amines and amino acids

Synthesis of functionalized mono-, bis-, and tris(spirophosphoranyl) amines and amino acids Full article

Journal

Russian Chemical Bulletin
ISSN: 1573-9171 , E-ISSN: 1066-5285

Output data

Year: 2025, Volume: 74, Number: 7, Pages: 2143-2155 Pages count : 13 DOI: 10.1007/s11172-025-4698-z

Authors

Bubnov Yu.N. ^1,2 , Prishchenko A.A. ³ , Livantsov M.V. ³ , Novikova O.P. ³ , Livantsova L.I. ³ , Baranin S.V. ²

Affiliations

1	A. N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, Build. 1, 28 ul. Vavilova, 119991, Moscow, Russian Federation
2	N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky prosp., 119991, Moscow, Russian Federation
3	Chemical Department, M. V. Lomonosov Moscow State University, Build. 3, 1 Leninskiye Gory, 119991, Moscow, Russian Federation

Convenient syntheses of functionalized PCH2N-containing mono-, bis-, and tris-(spirophosphoranylmethyl)amines and analogous amino acids based on hydrospirophosphoranes of the 1,4,6,9-tetraoxa-5λ5-phosphaspiro[4.4]nonane type using mono-, bis-, and tris-aminomethylating agents have been developed. Transesterification of diethyl esters of N,N-disubstituted aminomethylphosphonous acids with ethylene glycol is accompanied by a redox process and furnishes aminomethylspirophosphoranes. The target compounds are of interest as biologically active substances, polydentate chelating ligands, and also as promising monomers for the synthesis of phosphorus-containing polymers.

Bubnov Y.N. , Prishchenko A.A. , Livantsov M.V. , Novikova O.P. , Livantsova L.I. , Baranin S.V.
Synthesis of functionalized mono-, bis-, and tris(spirophosphoranyl) amines and amino acids
Russian Chemical Bulletin. 2025. V.74. N7. P.2143-2155. DOI: 10.1007/s11172-025-4698-z WOS Scopus OpenAlex

≡ Web of science:	WOS:001554001100002
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