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Scalable Synthesis of 1,5-Diazabicyclo[3.1.0]hexanes Using N-Chlorosuccinimide as Chlorinating Agent Научная публикация

Журнал Organic Letters
ISSN: 1523-7060 , E-ISSN: 1523-7052
Вых. Данные Год: 2025, Том: 27, Номер: 22, Страницы: 5686-5690 Страниц : 5 DOI: 10.1021/acs.orglett.5c01440
Авторы Vinogradova Ekaterina E. 1 , Fershtat Leonid L. 1
Организации
1 N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow 119991, Russian Federation

Реферат: An optimized synthetic approach toward the assembly of 1,5-diazabicyclo[3.1.0]hexanes (bicyclic diaziridines) was developed. This protocol involves the utilization of N-chlorosuccinimide as a convenient and easy-to-handle chlorinating agent, which in combination with carbonyl compounds and 1,3-diaminopropane enables a preparation of a wide set of target diaziridines. High yields, structural diversity and scalability demonstrate the broad applicability of this procedure for further investigations.
Библиографическая ссылка: Vinogradova E.E. , Fershtat L.L.
Scalable Synthesis of 1,5-Diazabicyclo[3.1.0]hexanes Using N-Chlorosuccinimide as Chlorinating Agent
Organic Letters. 2025. V.27. N22. P.5686-5690. DOI: 10.1021/acs.orglett.5c01440 WOS Scopus OpenAlex
Идентификаторы БД:
Web of science: WOS:001497483900001
Scopus: 2-s2.0-105006679277
OpenAlex: W4410774251
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