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Electrochemical Synthesis of Isoxazolines from Aldoximes and EWG-Substituted Alkenes Enabling by In Situ Generated Hypervalent Iodine Compounds Full article

Journal Russian Journal of Organic Chemistry
ISSN: 1608-3393 , E-ISSN: 1070-4280
Output data Year: 2025, Volume: 61, Number: 6, Pages: 1056-1065 Pages count : 10 DOI: 10.1134/s1070428025602213
Authors Bityukov O.V. 1,2 , Kirillov A.S. 2 , Vil’ V.A. 2 , Nikishin G.I. 2 , Terent’ev A.O. 2
Affiliations
1 All-Russian Research Institute for Phytopathology, B. Vyazyomy, 143050, Moscow Region, Russia
2 N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 119991, Moscow, Russia

Abstract: We developed the electrochemical synthesis of isoxazolines from aldoximes and EWG-substituted alkenes with the assistance of the in situ generated hypervalent iodine compounds. A wide range of substituted isoxazolines possessing fungicidal activity were obtained in 20–48% yields under constant current conditions in an undivided cell.
Cite: Bityukov O.V. , Kirillov A.S. , Vil’ V.A. , Nikishin G.I. , Terent’ev A.O.
Electrochemical Synthesis of Isoxazolines from Aldoximes and EWG-Substituted Alkenes Enabling by In Situ Generated Hypervalent Iodine Compounds
Russian Journal of Organic Chemistry. 2025. V.61. N6. P.1056-1065. DOI: 10.1134/s1070428025602213 WOS Scopus OpenAlex
Identifiers:
Web of science: WOS:001529083700019
Scopus: 2-s2.0-105010658713
OpenAlex: W4412372684
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