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Synthesis of new mono- and dinitroimidazo[1,2-a]pyridines Научная публикация

Журнал Russian Chemical Bulletin
ISSN: 1573-9171 , E-ISSN: 1066-5285
Вых. Данные Год: 2025, Том: 74, Номер: 1, Страницы: 115-119 Страниц : 5 DOI: 10.1007/s11172-025-4506-9
Авторы Kolyadina S.A. 1 , Bastrakov M.A. 1 , Starosotnikov A.M. 1
Организации
1 N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky prosp., 119991, Moscow, Russian Federation

Реферат: The study of the nitration of a number of imidazo[1,2-a]pyridines showed that the presence of a strong electron-donating substituent (OH, NH2) in the molecule is essential for the introduction of two nitro groups into the pyridine ring. On this basis, an approach to the synthesis of previously unknown 5,7- and 6,8-dinitroimidazo[1,2-a]pyridines was elaborated. In the case of electron-withdrawing substituents (Br), the reactions occurred predominantly at position 3 of the heterocyclic system. The obtained nitro derivatives are of interest as a basis for the synthesis of new polyfunctional imidazo[1,2-a]pyridines.
Библиографическая ссылка: Kolyadina S.A. , Bastrakov M.A. , Starosotnikov A.M.
Synthesis of new mono- and dinitroimidazo[1,2-a]pyridines
Russian Chemical Bulletin. 2025. V.74. N1. P.115-119. DOI: 10.1007/s11172-025-4506-9 WOS Scopus OpenAlex
Идентификаторы БД:
Web of science: WOS:001452513200028
Scopus: 2-s2.0-105001309370
OpenAlex: W4408935456
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