N,N′,N″-Trisubstituted hexahydro-1,3,5-triazine-based synthesis of mono- and diphosphorus-containing amino acids

N,N′,N″-Trisubstituted hexahydro-1,3,5-triazine-based synthesis of mono- and diphosphorus-containing amino acids Full article

Journal

Russian Chemical Bulletin
ISSN: 1573-9171 , E-ISSN: 1066-5285

Output data

Year: 2025, Volume: 74, Number: 3, Pages: 797-806 Pages count : 10 DOI: 10.1007/s11172-025-4573-y

Authors

Bubnov Yu.N. ^1,2 , Prishchenko A.A. ³ , Livantsov M.V. ³ , Novikova O.P. ³ , Livantsova L.I. ³ , Baranin S.V. ²

Affiliations

1	A. N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, Build. 1, 28 ul. Vavilova, 119991, Moscow, Russian Federation
2	N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky prosp., 119991, Moscow, Russian Federation
3	Chemical Department, M. V. Lomonosov Moscow State University, Build. 3, 1 Leninskiye Gory, 119991, Moscow, Russian Federation

Convenient syntheses of mono- and diphosphorus-containing amino acid derivatives based on 1,3,5-[ω-(alkoxycarbonyl)alkyl]hexahydro-1,3,5-triazines have been developed. The reaction of PH acids with readily available hexahydro-1,3,5-triazines and N-substituted bis(alkoxymethyl)amines obtained therefrom gives new mono- and diphosphorus-substituted amino acids containing P(O)CH2NH and P(O)CH2NCH2P(O) units together with glycine, β-alanine and γ-aminobutyric acid residues. The resulting compounds are of interest as promising biologically active substances, effective extractants, and water-soluble polydentate ligands.

Bubnov Y.N. , Prishchenko A.A. , Livantsov M.V. , Novikova O.P. , Livantsova L.I. , Baranin S.V.
N,N′,N″-Trisubstituted hexahydro-1,3,5-triazine-based synthesis of mono- and diphosphorus-containing amino acids
Russian Chemical Bulletin. 2025. V.74. N3. P.797-806. DOI: 10.1007/s11172-025-4573-y WOS Scopus OpenAlex

≡ Web of science:	WOS:001478277500014
≡ Scopus:	2-s2.0-105003879044
≡ OpenAlex:	W4409870709