Synthesis and functionalization of P(O)CH2NH- and P(O)CH2NSi-containing amines

Synthesis and functionalization of P(O)CH2NH- and P(O)CH2NSi-containing amines Full article

Journal

Russian Chemical Bulletin
ISSN: 1573-9171 , E-ISSN: 1066-5285

Output data

Year: 2025, Volume: 74, Number: 4, Pages: 1041-1054 Pages count : 14 DOI: 10.1007/s11172-025-4599-1

Authors

Bubnov Yu.N. ^1,2 , Prishchenko A.A. ³ , Livantsov M.V. ³ , Novikova O.P. ³ , Livantsova L.I. ³ , Baranin S.V. ²

Affiliations

1	A. N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, Build. 1, 28 ul. Vavilova, 119991, Moscow, Russian Federation
2	N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky prosp., 119991, Moscow, Russian Federation
3	Chemical Department, M. V. Lomonosov Moscow State University, Build. 3, 1 Leninskiye Gory, 119991, Moscow, Russian Federation

Convenient syntheses of phosphorus-substituted amines containing P(O)CH2NH and P(O)CH2NSi moieties based on the reaction between N,N′,N″-trisubstituted hexahydro-1,3,5-triazines and trivalent phosphorus acid esters have been developed. Various functionalization reactions (2-carboxyethylation, 2-pyridylethylation, and acylation) of the NH and NSi units of the resulting synthons proceed under mild conditions and give new functionalized phosphorus-containing amines in high yields. The resulting compounds are of interest as promising biologically active substances, water-soluble polydentate ligands, and effective extractants.

Bubnov Y.N. , Prishchenko A.A. , Livantsov M.V. , Novikova O.P. , Livantsova L.I. , Baranin S.V.
Synthesis and functionalization of P(O)CH2NH- and P(O)CH2NSi-containing amines
Russian Chemical Bulletin. 2025. V.74. N4. P.1041-1054. DOI: 10.1007/s11172-025-4599-1 WOS Scopus OpenAlex

≡ Web of science:	WOS:001489981900022
≡ Scopus:	2-s2.0-105005263741
≡ OpenAlex:	W4410396729