Реферат: The 1,2,5-oxadiazole ring is an important structural motif in the design of next-generation therapeutic agents and various functional materials. Although chemistry of 1,2,5-oxadiazoles has been known for a while, main recent efforts of researchers in this field are focused on the construction of heteroaryl-substituted 1,2,5-oxadiazoles. A combination of several heterocyclic moieties within a molecule usually provides a synergistic effect on functional properties of the resulting hybrids compared to their parent entities. In this Account, we summarize our recent achievements in the development of straightforward and step-economy methods for the synthesis of heteroaryl-1,2,5-oxadiazoles. Mostly, the presented approaches are based on heterocyclization and/or cycloaddition of 1,2,5-oxadiazole-derived precursors. Potential application perspectives of the presented compounds are also emphasized.

Библиографическая ссылка: Sidunets Y. , Fershtat L.
Advances in the Synthesis of Heteroaryl-1,2,5-oxadiazoles: A Personal Account
Synlett. 2025. DOI: 10.1055/a-2759-6787 WOS Scopus OpenAlex

Идентификаторы БД:

Web of science:	WOS:001639528100001
Scopus:	2-s2.0-105025012895
OpenAlex:	W4416822516

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БД	Цитирований
OpenAlex	Нет цитирований
Scopus	Нет цитирований

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