A one-pot method for the synthesis of acetyl derivatives of spiro-1,3,4-thiadiazolines

A one-pot method for the synthesis of acetyl derivatives of spiro-1,3,4-thiadiazolines Full article

Journal

Phosphorus, Sulfur and Silicon and the Related Elements
ISSN: 1042-6507 , E-ISSN: 1563-5325

Output data

Year: 2026, Volume: 201, Pages: 278-285 Pages count : 8 DOI: 10.1080/10426507.2025.2593402

Authors

Komkov Alexander V. ¹ , Menchikov Leonid G. ¹ , Dmitrenok Andrey S. ¹ , Nasyrova Darina I. ^2,1 , Zavarzin Igor V. ¹

Affiliations

1	N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences
2	Moscow Institute of Physics and Technology (MIPT) 9 Institutskiy per

A method for the synthesis of acetyl derivatives of spiro-1,3,4-thiadiazolines was developed involving a catalytic reaction of cyclic ketones with oxamic acid thiohydrazides in the presence of TsOH followed by acetylation.

Komkov A.V. , Menchikov L.G. , Dmitrenok A.S. , Nasyrova D.I. , Zavarzin I.V.
A one-pot method for the synthesis of acetyl derivatives of spiro-1,3,4-thiadiazolines
Phosphorus, Sulfur and Silicon and the Related Elements. 2026. V.201. P.278-285. DOI: 10.1080/10426507.2025.2593402 WOS Scopus OpenAlex

Submitted:	Jul 16, 2025
Published online:	Dec 14, 2025

≡ Web of science:	WOS:001638984000001
≡ Scopus:	2-s2.0-105024873760
≡ OpenAlex:	W7115184299