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Electrochemically induced multicomponent ‘one-pot’ assembling benzaldehydes, N,N′-dimethylbarbituric acid, and kojic acid Научная публикация

Журнал Monatshefte Fur Chemie
ISSN: 1434-4475 , E-ISSN: 0026-9247
Вых. Данные Год: 2020, Том: 151, Номер: 4, Страницы: 567-573 Страниц : 7 DOI: 10.1007/s00706-020-02578-6
Авторы Elinson Michail N. 1 , Ryzhkova Yuliya E. 1 , Krymov Stepan K. 2 , Vereshchagin Anatoly N. 1 , Goloveshkin Alexander S. 3 , Egorov Mikhail P. 1
Организации
1 N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russian Federation
2 D. I, Mendeleev University of Chemical Technology, Moscow, Russian Federation
3 A. N. Nesmeyanov Organoelement Compounds Institute, Russian Academy of Sciences, Moscow, Russian Federation

Реферат: The new electrochemically induced multicomponent assembling was found: the electrocatalytic transformation of benzaldehydes, N,N′-dimethylbarbituric acid, and kojic acid has been carried out in alcohols in an undivided cell in the presence of sodium halides with the selective formation of the earlier unknown substituted 5-[[3-hydroxy-6-(hydroxymethyl)-4-oxo-4H-pyran-2-yl](phenyl)methyl]-1,3-dimethylpyrimidine-2,4,6(1H,3H,5H)-triones in 65–88% yields and with 325–440% current efficiency. This new multicomponent process provides facile and efficient way to the novel type of separated by C-aryl-substituted spacer both 4-oxo-4H-pyran and 1,3-dimethylpyrimidine-2,4,6(1H,3H,5H)-trione pharmacology active systems, which are promising compounds for different biomedical applications.
Библиографическая ссылка: Elinson M.N. , Ryzhkova Y.E. , Krymov S.K. , Vereshchagin A.N. , Goloveshkin A.S. , Egorov M.P.
Electrochemically induced multicomponent ‘one-pot’ assembling benzaldehydes, N,N′-dimethylbarbituric acid, and kojic acid
Monatshefte Fur Chemie. 2020. V.151. N4. P.567-573. DOI: 10.1007/s00706-020-02578-6 WOS Scopus OpenAlex
Идентификаторы БД:
Web of science: WOS:000529874700001
Scopus: 2-s2.0-85084126338
OpenAlex: W3021847186
Цитирование в БД:
БД Цитирований
OpenAlex 6
Scopus 6
Web of science 5
Альметрики: