Structure and gene cluster of the capsular polysaccharide of Acinetobacter baumannii K223

Structure and gene cluster of the capsular polysaccharide of Acinetobacter baumannii K223 Научная публикация

Журнал

Carbohydrate Research
ISSN: 1873-426X , E-ISSN: 0008-6215

Вых. Данные

Год: 2026, Том: 563, Номер статьи : 109846, Страниц : DOI: 10.1016/j.carres.2026.109846

Авторы

Filatov Andrei V. ¹ , Shpirt Anna M. ¹ , Perepelov Andrei V. ¹ , Dmitrenok Andrei S. ¹ , Shneider Mikhail M. ² , Avdeeva Victoria A. ³ , Toukach Philip V. ¹ , Knirel Yuriy A. ¹

Организации

1	N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russia
2	M. M. Shemyakin & Y. A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia
3	State Research Center for Applied Microbiology and Biotechnology, Obolensk, Russia

Structure of the Acinetobacter baumannii strain MAR22-475 classified to KL223 type capsular polysaccharide (CPS) was established by component analyses, Smith degradation as well as 1H and 13C NMR spectroscopy, including two-dimensional homonuclear 1Н,1Н COSY, TOCSY, ROESY and heteronuclear 1Н,13C HSQC and HMBC experiments. The K223 CPS is composed of branched tetrasaccharide K-units containing two d-Glсp residues, and one residue each of d-GlcpNAc and d-Galp. The following structure of the tetrasaccharide repeating unit of the CPS was established:

Filatov A.V. , Shpirt A.M. , Perepelov A.V. , Dmitrenok A.S. , Shneider M.M. , Avdeeva V.A. , Toukach P.V. , Knirel Y.A.
Structure and gene cluster of the capsular polysaccharide of Acinetobacter baumannii K223
Carbohydrate Research. 2026. V.563. 109846 . DOI: 10.1016/j.carres.2026.109846 WOS Scopus OpenAlex

Поступила в редакцию:	3 дек. 2025 г.
Опубликована online:	6 февр. 2026 г.

Web of science:	WOS:001686502400001
Scopus:	2-s2.0-105029282725
OpenAlex:	W7125934560

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