Synthesis of oxo dihydro pyrrolo[1,2-a]quinazoline and benzo[e]pyrrolo[1,2-b][1,2,4]triazepine carboxylic acids

Synthesis of oxo dihydro pyrrolo[1,2-a]quinazoline and benzo[e]pyrrolo[1,2-b][1,2,4]triazepine carboxylic acids Full article

Journal

Mendeleev Communications
ISSN: 1364-551X , E-ISSN: 0959-9436

Output data

Year: 2026, Volume: 36, Pages: 335-337 Pages count : 3 DOI: 10.71267/mencom.7922

Authors

Serkov Sergei A. ¹ , Sigay Natalya V. ¹ , Kostikova Natalya N. ¹ , Kolotyrkina Natalya Georgievna ¹ , Gazieva Galina Anatol'evna ¹

Affiliations

1	N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 119991 Moscow, Russian Federation

Two new heterocyclic carboxylic acids, namely, 2-carboxy derivatives of naturally occurring 2,3-dihydropyrrolo[1,2-a]quinazoline-5(1H)-one and potentially biologically active 2,3-dihydro-1H-benzo[e]pyrrolo[1,2-b][1,2,4]triazepin- 6(5H)-one, have been synthesized by the fusion of itaconic acid with anthranilic acid amide or hydrazide, respectively, in one or two steps in moderate to high yields.

Serkov S.A. , Sigay N.V. , Kostikova N.N. , Kolotyrkina N.G. , Gazieva G.A.
Synthesis of oxo dihydro pyrrolo[1,2-a]quinazoline and benzo[e]pyrrolo[1,2-b][1,2,4]triazepine carboxylic acids
Mendeleev Communications. 2026. V.36. P.335-337. DOI: 10.71267/mencom.7922 WOS Scopus OpenAlex

Submitted:	Sep 22, 2025
Accepted:	Nov 20, 2025
Published online:	Mar 24, 2026

≡ Web of science:	WOS:001755710600027
≡ Scopus:	2-s2.0-105034307661
≡ OpenAlex:	W7128788042