Synthesis of Polyalkoxymethylenedioxy-1,4-naphthoquinones from Parsley Seed Metabolite

Synthesis of Polyalkoxymethylenedioxy-1,4-naphthoquinones from Parsley Seed Metabolite Full article

Journal

Current Organic Chemistry
ISSN: 1385-2728 , E-ISSN: 1875-5348

Output data

Year: 2024, Volume: 28, Number: 1, Pages: 40-45 Pages count : 6 DOI: 10.2174/0113852728283175231218092342

Authors

Varakutin A.E. ¹ , Muravsky E.A. ¹ , Khrustalev V.N. ^1,2 , Samet A.V. ¹ , Semenov V.V. ¹

Affiliations

1	N.D. Zelinsky Institute of Organic Chemistry RAS, 47 Leninsky Prospect, 119991 Moscow, Russian Federation
2	Department of Organic Chemistry, RUDN University, 6 Miklukho-Maklay Street, 117198 Moscow, Russian Federation

A convenient synthesis of polyalkoxy-1,4-naphthoquinones, good starting materials for analogues of natural quinones, has been developed. Bromonaphthoquinone, more stable than its hydroxylated analogue, turned out to be a convenient and accessible key synthon for the preparation of various polyalkoxylated naphthoquinones. The obtained quinones could be useful starting materials for the preparation of biologically active polymethoxy- and hydroxy-methylenedioxynaphthoquinones.

Varakutin A.E. , Muravsky E.A. , Khrustalev V.N. , Samet A.V. , Semenov V.V.
Synthesis of Polyalkoxymethylenedioxy-1,4-naphthoquinones from Parsley Seed Metabolite
Current Organic Chemistry. 2024. V.28. N1. P.40-45. DOI: 10.2174/0113852728283175231218092342 WOS Scopus OpenAlex

Web of science:	WOS:001186242000002
Scopus:	2-s2.0-85184927480
OpenAlex:	W4390343337

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