Synthesis of functionalized mono- and bisphosphorus-containing methylamines based on aminoacetals and their analogs

Synthesis of functionalized mono- and bisphosphorus-containing methylamines based on aminoacetals and their analogs Full article

Journal

Russian Chemical Bulletin
ISSN: 1573-9171 , E-ISSN: 1066-5285

Output data

Year: 2026, Volume: 75, Number: 1, Pages: 306-321 Pages count : 16 DOI: 10.1007/s11172-026-4888-3

Authors

Bubnov Yu.N. ^1,2 , Prishchenko A.A. ² , Livantsov M.V. ³ , Novikova O.P. ³ , Livantsova L.I. ³ , Baranin S.V. ²

Affiliations

1	A. N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, Build. 1, 28 ul. Vavilova, 119991, Moscow, Russian Federation
2	N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky prosp., 119991, Moscow, Russian Federation
3	Chemical Department, M. V. Lomonosov Moscow State University, Build. 3, 1 Leninskiye Gory, 119991, Moscow, Russian Federation

Convenient syntheses of functionalized mono- and bisphosphorus-substituted methylamines and their derivatives, containing P—C—N and P—C(N)—P units, based on aminoacetals and their analogs have been developed. Dialkoxyphosphines, diethyl pivaloylphosphonite, diethyl phosphite, or trivalent phosphorus acid trimethylsilyl esters react with mono- and bis(alkoxymethyl)amines in the presence of effective catalysts, zinc chloride or boron trifluoride etherate, to afford new target products in high yields. The resulting substances, functionalized mono- and bisphosphorus-containing methylamines, are structural analogs of amino carboxylic acids and natural pyrophosphates and are of interest as promising biologically active substances, water-soluble polydentate ligands, and effective extractants.

Bubnov Y.N. , Prishchenko A.A. , Livantsov M.V. , Novikova O.P. , Livantsova L.I. , Baranin S.V.
Synthesis of functionalized mono- and bisphosphorus-containing methylamines based on aminoacetals and their analogs
Russian Chemical Bulletin. 2026. V.75. N1. P.306-321. DOI: 10.1007/s11172-026-4888-3 WOS Scopus OpenAlex

Бубнов Ю.Н. , Прищенко А.А. , Ливанцов М.В. , Новикова О.П. , Ливанцова Л.И. , Баранина С.В.
Синтез функционализированных моно- и бисфосфорсодержащих метиламинов на основе аминоацеталей и их аналогов
Известия Академии наук. Серия химическая. 2026. Т.75. №1. С.306-321.

Submitted:	Jun 26, 2025
Published online:	Mar 30, 2026

≡ Web of science:	WOS:001746150700027
≡ Scopus:	2-s2.0-105034931951
≡ OpenAlex:	W7143752298