Novel Synthesis of Benzo[e][1,2,4]triazines via Cyclocondensation of Azooximes Full article
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Advanced Synthesis & Catalysis
ISSN: 1615-4169 , E-ISSN: 1615-4150 |
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| Output data | Year: 2026, Volume: 368, Number: 10, Article number : e70430, Pages count : DOI: 10.1002/adsc.70430 | ||
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Abstract:
An approach for the selective synthesis of benzo[e][1,2,4]triazines from readily accessible azooximes is described. The method is based on cyclocondensation reaction performed at room temperature in the presence of trifluoroacetic anhydride and methanesulfonic acid. The process leads to specifically substituted benzo[e][1,2,4]triazines, which can serve as precursors of stable Blatter radicals. The method features inexpensive and readily available starting materials, broad substrate scope, mild and metal-free reaction conditions, and versatile functionalization of the 1,2,4-benzotriazines.
Cite:
Frumkin A.E.
, Dilman A.D.
Novel Synthesis of Benzo[e][1,2,4]triazines via Cyclocondensation of Azooximes
Advanced Synthesis & Catalysis. 2026. V.368. N10. e70430 . DOI: 10.1002/adsc.70430 WOS Scopus OpenAlex
Novel Synthesis of Benzo[e][1,2,4]triazines via Cyclocondensation of Azooximes
Advanced Synthesis & Catalysis. 2026. V.368. N10. e70430 . DOI: 10.1002/adsc.70430 WOS Scopus OpenAlex
Dates:
| Submitted: | Jan 31, 2026 |
| Published online: | May 21, 2026 |
Identifiers:
| ≡ Web of science: | WOS:001770782600001 |
| ≡ Scopus: | 2-s2.0-105039516040 |
| ≡ OpenAlex: | W7161966333 |