Synthesis and X-ray diffraction analysis of coenzyme Q derivatives obtained from natural polyalkoxyallylbenzenes

Synthesis and X-ray diffraction analysis of coenzyme Q derivatives obtained from natural polyalkoxyallylbenzenes Full article

Journal

Mendeleev Communications
ISSN: 1364-551X , E-ISSN: 0959-9436

Output data

Year: 2023, Volume: 33, Number: 4, Pages: 539-542 Pages count : 4 DOI: 10.1016/j.mencom.2023.06.032

Authors

Tsyganov Dmitry V. ¹ , Demchuk Dmitry V. ¹ , Adaeva Olga I. ¹ , Konyushkin Leonid D. ¹ , Minyaev Mikhail E. ¹ , Khrustalev Victor N. ^1,2 , Semenov Victor V. ¹

Affiliations

1	N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 119991 Moscow, Russian Federation
2	Peoples Friendship University of Russia (RUDN University), 117198 Moscow, Russian Federation

A general synthetic access to methoxy analogues of coenzymes Q bearing functional substituents with various chain lengths at the quinone ring was developed using available natural (polymethoxy)(methylenedioxy)allylbenzenes. The Baeyer–Villiger rearrangement of (methylenedioxy)benzaldehydes into phenols followed by facile oxidation to quinones with the methylenedioxy moiety opening was identified as the key step in the synthesis of the target 1,4- and 1,2-polyalkoxyquinones.

Tsyganov D.V. , Demchuk D.V. , Adaeva O.I. , Konyushkin L.D. , Minyaev M.E. , Khrustalev V.N. , Semenov V.V.
Synthesis and X-ray diffraction analysis of coenzyme Q derivatives obtained from natural polyalkoxyallylbenzenes
Mendeleev Communications. 2023. V.33. N4. P.539-542. DOI: 10.1016/j.mencom.2023.06.032 WOS Scopus OpenAlex

Web of science:	WOS:001044224700001
Scopus:	2-s2.0-85166547688
OpenAlex:	W4384501472

DB	Citing
OpenAlex	6
Scopus	6
Web of science	5