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Light-Promoted Radical Arylation of Nitrones with Triazenes Full article

Journal Organic Letters
ISSN: 1523-7060 , E-ISSN: 1523-7052
Output data Year: 2026, Volume: 28, Number: 24, Pages: 7651-7654 Pages count : 4 DOI: 10.1021/acs.orglett.6c01780
Authors Supranovich Vyacheslav I. 1 , Dilman Alexander D. 1
Affiliations
1 N. D. Zelinsky Institute of Organic Chemistry, 119991 Moscow, Leninsky prosp. 47, Russian Federation

Abstract: Application of aryltriazenes as safe precursors of aryl radicals for the direct hydroarylation of nitrones, furnishing substituted hydroxylamines, is described. The reaction proceeds under visible-light irradiation using sodium ascorbate as a reductant and acetic acid as a proton source. Light-induced E to Z isomerization of triazenes, which results in enhanced reactivity of the Z-isomer and eliminates the need for a photocatalyst, is a key feature of the method. The scope of the triazene component is limited to electron-rich and neutral aryls.
Cite: Supranovich V.I. , Dilman A.D.
Light-Promoted Radical Arylation of Nitrones with Triazenes
Organic Letters. 2026. V.28. N24. P.7651-7654. DOI: 10.1021/acs.orglett.6c01780 WOS Scopus OpenAlex
Dates:
Submitted: Apr 22, 2026
Accepted: Jun 4, 2026
Published online: Jun 8, 2026
Identifiers:
≡ Web of science: WOS:001787397200001
≡ Scopus: 2-s2.0-105042400314
≡ OpenAlex: W7163906264
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