Structure and gene cluster of the capsular polysaccharide of Acinetobacter baumannii K205

Structure and gene cluster of the capsular polysaccharide of Acinetobacter baumannii K205 Full article

Journal

Carbohydrate Research
ISSN: 1873-426X , E-ISSN: 0008-6215

Output data

Year: 2026, Volume: 568, Article number : 110025, Pages count : DOI: 10.1016/j.carres.2026.110025

Authors

Filatov Andrei V. ¹ , Perepelov Andrei V. ¹ , Shpirt Anna M. ¹ , Dmitrenok Andrei S. ¹ , Shneider Mikhail M. ² , Mikhailova Yulia V. ³ , Shelenkov Andrey A. ³ , Knirel Yuriy A. ¹

Affiliations

1	N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russia
2	M. M. Shemyakin & Y. A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia
3	Central Scientific Research Institute of Epidemiology, Moscow, Russia

Structure of the Acinetobacter baumannii strain MAR22-3311 classified to KL205 type capsular polysaccharide (CPS) was established by component analyses, Smith degradation as well as 1H and 13C NMR spectroscopy, including two-dimensional homonuclear 1Н,1Н COSY, TOCSY, ROESY and heteronuclear 1Н,13C HSQC and HMBC experiments. The K205 CPS is composed of branched hexasaccharide K-units containing three d-GalNAc residues, and one residue each of d-Quip3NAc, d-Galp and d-Glcp. The following structure of the hexasaccharide repeating unit of the CPS was established. Functions of genes in the K locus of A. baumannii MAR22-3311 (K205) were assigned by a comparison with sequences in the available databases and found to be in agreement with the CPS structure.

Filatov A.V. , Perepelov A.V. , Shpirt A.M. , Dmitrenok A.S. , Shneider M.M. , Mikhailova Y.V. , Shelenkov A.A. , Knirel Y.A.
Structure and gene cluster of the capsular polysaccharide of Acinetobacter baumannii K205
Carbohydrate Research. 2026. V.568. 110025 . DOI: 10.1016/j.carres.2026.110025 Scopus OpenAlex

Submitted:	May 26, 2026
Published online:	Jul 10, 2026

≡ Scopus:	2-s2.0-105043974395
≡ OpenAlex:	W7167041861