Glycoluril derivatives bearing four quaternary pyridinium moieties as a new type of cationic biocides

Glycoluril derivatives bearing four quaternary pyridinium moieties as a new type of cationic biocides Full article

Journal

Mendeleev Communications
ISSN: 1364-551X , E-ISSN: 0959-9436

Output data

Year: 2026, Volume: 36, Number: 6, Pages: 715-717 Pages count : 3 DOI: 10.71267/mencom.8113

Authors

Seferyan Mary A ¹ , Valeev Anver B ^2,1 , Sinikin Egor V ^2,1 , Frolov Nikita Andreevich ¹ , Detusheva Elena Vladimirovna ^1,3 , Vereshchagin Anatoly Nikolaevich ¹

Affiliations

1	N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 119991 Moscow, Russian Federation
2	D. I. Mendeleev University of Chemical Technology of Russia, 125047 Moscow, Russian Federation
3	State Research Center for Applied Microbiology & Biotechnology, 142279 Obolensk, Moscow Region, Russian Federation

New type of tetracationic biocides, glycoluril derivatives bearing four quaternary pyridinium moieties (in turn, containing 4-alkylamino substituents), were synthesized starting from diethyl carbonate and 3-aminopropanol. The microbiological studies (assessed against reference and multidrug-resistant strains from ESKAPE pathogens in both planktonic and biofilm forms) show that these salts exhibit antibacterial activity against all of studied microorganisms comparable to those of commercial antiseptics.

Seferyan M.A. , Valeev A.B. , Sinikin E.V. , Frolov N.A. , Detusheva E.V. , Vereshchagin A.N.
Glycoluril derivatives bearing four quaternary pyridinium moieties as a new type of cationic biocides
Mendeleev Communications. 2026. V.36. N6. P.715-717. DOI: 10.71267/mencom.8113 OpenAlex

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