Highly diastereoselective multicomponent synthesis of pyridinium-substituted piperidin-2-ones with three stereogenic centres

Highly diastereoselective multicomponent synthesis of pyridinium-substituted piperidin-2-ones with three stereogenic centres Научная публикация

Журнал

Mendeleev Communications
ISSN: 1364-551X , E-ISSN: 0959-9436

Вых. Данные

Год: 2023, Том: 33, Номер: 6, Страницы: 762-763 Страниц : 2 DOI: 10.1016/j.mencom.2023.10.007

Авторы

Vinokurov Andrey D. ¹ , Iliyasov Taygib M. ¹ , Karpenko Kirill A. ¹ , Evstigneeva Alexandra V. ^1,2 , Minaeva Alexandra P. ¹ , Elinson Michail N. ¹ , Vereshchagin Anatoly N. ¹

Организации

1	N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 119991, Moscow, Russian Federation
2	National Research University Higher School of Economics (HSE University), 101000, Moscow, Russian Federation

The Michael–Mannich–cyclization cascade of dicyano olefins, 1-(2-alkoxy-2-oxoethyl)pyridin-1-ium halogenides, aromatic aldehydes and ammonium acetate provides convenient stereoselective formation of (4,6-diaryl-5,5-dicyano-2-oxo-piperidin-3-yl)pyridin-1-ium halogenides with three stereogenic centres. Ammonium acetate plays dual role acting as a base and as a nitrogen source.

Vinokurov A.D. , Iliyasov T.M. , Karpenko K.A. , Evstigneeva A.V. , Minaeva A.P. , Elinson M.N. , Vereshchagin A.N.
Highly diastereoselective multicomponent synthesis of pyridinium-substituted piperidin-2-ones with three stereogenic centres
Mendeleev Communications. 2023. V.33. N6. P.762-763. DOI: 10.1016/j.mencom.2023.10.007 WOS Scopus OpenAlex

Web of science:	WOS:001128187900001
Scopus:	2-s2.0-85183747381
OpenAlex:	W4389121493

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OpenAlex	1
Scopus	1
Web of science	1